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High School, Microbiology Projects, Lessons, Activities (24 results)

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Science Fair Project Idea
Scientific Method
Ultraviolet light can damage DNA molecules. If a cell's DNA repair mechanisms can't keep up with the damage, mutations are the result. As harmful mutations accumulate, the cell eventually dies. How much ultraviolet light is too much for a bacterial cell? Read more
Science Fair Project Idea
Scientific Method
Have you ever wondered if a piece of jewelry is real gold or if it's just some ordinary metal alloy? It turns out that some metals have a unique property; even in small amounts, they can be toxic to some organisms, including algae, molds, fungi, and bacteria, although it often takes many hours to see an effect. Can this phenomena, called the oligodynamic effect be used to tell whether or not the gold or silver in a piece of jewelry is real? Do bacteria react differently to pure, plated, and… Read more
Science Fair Project Idea
Scientific Method
Have you ever wondered where acne comes from and how you can treat it? One major cause of acne is the colonization and infection of clogged pores with bacteria. In this science project, you'll test different acne medications and treatments to determine their effectiveness at killing bacteria. Read more
Science Fair Project Idea
Scientific Method
Most people are not aware that the soil around them is a battle scene. The combatants are very small—bacteria on one side and bacteriophage on the other. The bacteriophage (or phage for short) try to pierce the outer coats of the bacteria and inject them with phage DNA. If successful, the DNA will take over the inner machinery of the bacterial cells and force them to make many copies of the phage. After the copies are made, the bacterial cells break apart, releasing new phage that start… Read more
Science Fair Project Idea
Scientific Method
Disinfectants are products that kill harmful bacteria that inhabit surfaces. Disinfectants can be in household and personal cleaning products. Which products work best? Compare different household cleaning products, like bleach or Lysol, to see which ones kill the most bacteria. Compare different brands of antibacterial hand soap or dish soap to see which brand is the most effective. How do hand sanitizers work? Compare rub-on hand sanitizers to see if they work better than alcohol, or compare… Read more
Science Fair Project Idea
Scientific Method
This is a project that illustrates the process of natural selection in action. You'll need access to a laboratory for working with the bacterial cultures used in this project. Read more
Science Fair Project Idea
Scientific Method
What do pneumonia, ear infections and strep throat have in common? When they are caused by bacteria (instead of viruses) they are treated by antibiotics. That sounds simple enough, right? You have probably had antibiotics several times in your life. You go to the doctor because you feel lousy, if he or she determines you have a bacterial infection you get a prescription for antibiotics, and within the first day or so you often start feeling much better. Unfortunately, there is a large… Read more
Lesson Plan Grade: 9th-12th
Students become biomedical engineers and create model viruses for use in therapeutic applications, such as gene therapy. In constructing their models, students carefully plan for side effects and modify a virus that can be used to safely to deliver gene therapy. This process involves taking a "wild type" (or unmodified) virus so it can target a specific area of the body.Engineering Connection Genetic engineering is the artificial manipulation, modification, and… Read more
NGSS Performance Expectations:
  • HS-ETS1-2. Design a solution to a complex real-world problem by breaking it down into smaller, more manageable problems that can be solved through engineering.
Science Fair Project Idea
Scientific Method
The Pilobolus fungus has an interesting way of making sure the next generation has a good start on life. At high speed, the fungus shoots a sac that contains spores toward a light source. Why toward a light source? Because that is where it is most likely to find an open area with grass. Once the spore is placed on grass, it is eaten by a cow or a horse, which is a critical step in its life cycle. The spore passes through the animal's digestive track and ends up in a pile of manure. For a fungal… Read more
Science Fair Project Idea
Scientific Method
Have you ever heard that nanoparticles can kill bacteria? You may have even seen some consumer products advertise that they contain antibacterial nanoparticles. A nanometer is one billionth of a meter long. Nanoparticles are usually just a few nanometers in diameter — really, really tiny! So how can something that small kill bacteria which are approximately 700 - 1400 nanometers across? Are they really effective? In this science project you will grow some E. coli bacteria and… Read more
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