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High School, Microbiology Projects, Lessons, Activities (24 results)

Microorganisms are all around us, with an amazing diversity of adaptations. They were the first life on Earth, and their relatively recent discovery in extreme environments—like hot springs, ocean vents, and polar ice—illustrates how tenaciously they've evolved and survived. Microbiology gives us insights into evolution, disease, and even the mechanisms of our own cells.

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Measuring Antimicrobial Effectiveness with Zones of Inhibition
Science Fair Project Idea
Scientific Method
Have you heard that garlic powder is supposed to inhibit the growth of bacteria? Which do you think would make a better disinfectant: a solution of garlic powder or a solution of bleach? This project shows you a straightforward way to compare the effectiveness of different disinfectants (or other antimicrobial agents), by measuring zones of inhibition on a culture plate. Read more
Make Your Own Hand Sanitizer
STEM Activity
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34 reviews
Did you ever wonder what hand sanitizer is made of, or how you can efficiently disinfect your hands or other frequently touched surfaces like doorknobs? Handwashing is still the best way to keep your hands clean, but hand sanitizer is a great alternative for situations where clean water and soap are not available, and you can even use it to disinfect surfaces! Intrigued—try out making a hand sanitizer yourself! Read more
How Do Bacteria Produce Power in a Microbial Fuel Cell?
Science Fair Project Idea
Scientific Method
Bacteria are powerful little creatures. They can dispose of contaminants, make us sick and did you know they can even generate electricity? In devices, called microbial fuel cells (MFC) they can extract electrons from their food sources such as organic materials and feed them into an electrical circuit to generate power. This way they can even turn plain soil into a source of energy! Does it matter though what kind of food the bacteria "eat"? Find out how bacteria grow in a microbial fuel cell… Read more
Antibiotic Resistance
Science Fair Project Idea
Scientific Method
Antibiotics work by destabilizing the metabolism or cellular structure of bacteria, preventing growth, and causing bacteria to die. Some strains of bacteria have mutated and found a way to resist the actions of antibiotics. These are called resistant strains because they resist the actions of available antibiotic treatments. There are many different types of antibiotics that are continually being developed to combat new strains of resistant bacteria. Some antibiotics work better on different… Read more
Do Antibiotics Change Your Gut Microbiome?
Science Fair Project Idea
Scientific Method
There are thousands of bacteria in your gut that help you digest your food, recover important nutrients, and maintain your health. What happens to those bacteria when you take antibiotics? In this science project you will find out by accessing and analyzing a real data set of the gut microbiome (bacteria and other microbes) from healthy adults before and after they are given antibiotics. Read more
Grow Vegan Kombucha Leather
Science Fair Project Idea
Scientific Method
Do you love the look and feel of leather? Many luxury items like handbags, belts, wallets, and coats are made from leather. What if you could make your own vegan leather in a few weeks? Could it be a greener, more sustainable option than cowhide leather? In this science project, you will grow your own vegan leather from kombucha and see how different growing conditions affect the resulting leather. Read more
Learn How to Disinfect Contaminated Water
Science Fair Project Idea
Scientific Method
Have you ever thought about how fortunate you are to have safe and clean water coming out of your faucet? Many people in undeveloped nations don't have this luxury. But does that mean they can't have clean water at all? Is there an inexpensive way they could use to make their own clean water? In this microbiology science fair project, you will investigate whether or not sunlight can disinfect contaminated water. Read more
What Sugar And Tea Does a Kombucha Biofilm Prefer?
Science Fair Project Idea
Scientific Method
You may have seen kombucha at the grocery store marketed as a healthy food choice. Did you know this drink is made with a special biofilm that ferments sugar into the tangy, fizzy drink? How does it do that? In this experiment, you'll learn how to make your own kombucha from a biofilm and what tea or sugar substrates you can change! Read more
An Aerobic Exercise: Yeast Metabolism with and without Aeration
Science Fair Project Idea
Scientific Method
This is a straightforward project on glucose metabolism in yeast. You will grow yeast under aerobic and anaerobic conditions and measure carbon dioxide output to assess metabolic efficiency. Read more
Cinnamon Gum and Mouth Microbes
Science Fair Project Idea
Scientific Method
Did you know that a scientific study has shown that chewing Big Red Gum reduces mouth microbes? (ScienceDaily contributors, 2004) The cinnamon oil in the gum is a natural defense against mouth bacteria that cause tooth decay and bad breath. Conduct an experiment to compare products with cinnamon essence in gum, candy, toothpaste, and mouthwash to see if they can decrease mouth germs. Do a before and after swab of the mouth with a Q-tip. Which treatments work the best? Can you find another… Read more
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