Twelfth Grade Projects, Lessons, Activities (Page 25)

Catalytic RNA and Structure

Science Fair Project Idea

Scientific Method

Some sequences of RNA can catalyze biochemical reactions, much like protein enzymes. These catalytic RNA sequences are called ribozymes. The function of a ribozyme depends upon the primary sequence of the RNA which folds into a 3-D structure. How do different ribozyme sequences fold? You can search for ribozyme sequences using Entrez BLAST (NCBI, 2006). Then you can use a program like MFOLD (http://bioweb.pasteur.fr/seqanal/interfaces/mfold-simple.html) to submit your sequence for an… Read more

Chain Reaction: Inversion and the Pappus Chain Theorem

Science Fair Project Idea

Scientific Method

Here is a challenging problem for anyone with an interest in geometry. This project requires background research to solve it, but it is an excellent illustration of visual thinking in mathematics. Figure 1 below shows a series of circles (iC₁, iC₂, iC₃, ..., iC₃₀), inscribed inside an arbelos. What is an arbelos? The arbelos is the white region in the figure, bounded by three semicircles. The diameters of the three semicircles are all on the same line segment, AC,… Read more

Coastal and Marine Geology

Science Fair Project Idea

Scientific Method

You can study hazards that affect coastal areas. What geological forces cause a tsunami? A tsunami (Japanese for 'harbor wave') is a wave generated by an undersea earthquake, landslip, or volcanic eruption. You can demonstrate what causes a tsunami by simulating an undersea earthquake with a water table. How does the depth of water effect the height of the wave? Do different slopes of bottom change the speed of the wave? Visit the USGS Coastal and Marine Geology Program to find out about… Read more

Comparing COVID-19 Variants: A Real-World Look at the Effect of Mutations

Lesson Plan Grade: 6th-12th

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We hear about COVID-19 variants all the time, but what is a virus variant, how do they come about, and why do they matter? Students will explore these question and more in this lesson plan. They will use SimPandemic, a free online tool, to model what COVID-19 outbreaks look like when communities are exposed to different COVID-19 variants and understand how genetic mutations in a virus can lead to functional changes. Read more

NGSS Performance Expectations:

MS-LS2-4. Construct an argument supported by empirical evidence that changes to physical or biological components of an ecosystem affect populations.
MS-LS3-1. Develop and use a model to describe why structural changes to genes (mutations) located on chromosomes may affect proteins and may result in harmful, beneficial, or neutral effects to the structure and function of the organism.
HS-LS3-2. Make and defend a claim based on evidence that inheritable genetic variations may result from (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, and/or (3) mutations caused by environmental factors.

Computational Exploration of Protein Function

Science Fair Project Idea

Scientific Method

The DNA in our cells contains our "blueprints," but it's the proteins in our cells that do most of the work. The Human Genome Project has allowed us to start reading the blueprints, but we still don't understand what most of the proteins do. This is a fairly advanced project that explores ways of identifying the function of unknown proteins. Read more

Computer Simulation of an Artificial Neural Network

Lesson Plan Grade: 9th-12th

Using the Netlogo platform to run simulations of a basic neural network called the perceptron, students explore a basic, yet powerful, model of machine learning as they are challenged to understand the logic. Students engage in the perceptron model and discover a weakness of the model. The students then move on to run simulations on Netlogo with the multi-layer perceptron which overcomes the weakness in the original perceptron model. Engineering Connection Machine learning… Read more

Cricket Wicket Knockdown Challenge for Grades 9-12

Lesson Plan Grade: 9th-12th

Teach your students about the engineering design process with this fun lesson plan. They will design and build a ball-launching machine to knock down a target. Optionally, they can enter their designs in the 2020 Engineering Challenge for a chance to win a cash prize for your school! Teachers, note that elementary school and middle school versions of this lesson plan are also available. Read more

NGSS Performance Expectations:

High School - Science & Engineering Practices

Data Models

Science Fair Project Idea

Scientific Method

Math is used by many different types of scientists to model phenomenon and evaluate data from an experiment. By building mathematical models scientists can understand how different physical, chemical, and biological processes are affected by different variables. The most important tools are: making a graph to give a visual representation of the relationships between your variables and making an equation to give a way of computing the relationships between your variables. Find a source of data,… Read more

Design Your Own 3D Optical Illusions

Lesson Plan Grade: 8th-12th

In this lesson your students will design their own 3D objects that exhibit "anomalous mirror symmetry"—that is, their reflections appear flipped left to right when you put them in front of a mirror. Students will start by defining the outline of a 2D shape using functions. They will then use MATLAB or Python code to convert the 2D shape into a 3D curve that replicates the outline of the 2D shape when viewed from a certain angle. Finally, they will convert the 3D curve into a solid 3D… Read more

Digital Image Processing

Science Fair Project Idea

Scientific Method

Students who are mathematically inclined can use the student version of a program like MatLab or Mathematica to convert a digital image into numbers, then perform operations such as sharpening or special effects. This is a great way to learn about image processing algorithms. Read more

Twelfth Grade Projects, Lessons, Activities (313 results)

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