High School, Biotechnology Science Projects (19 results)

Yogurt, biofuel, biodegradable plastics, and antibiotics are all examples of products based on biotechnology research and manufacturing techniques. What else will we be able to create as we use biotechnology in new ways?

Genetically Modified Organisms: Create Glowing Bacteria!

Science Fair Project Idea

Scientific Method

Have you ever heard or read about GMO? GMO stands for genetically modified organisms. Scientists can deliberately modify the DNA of organisms, such as bacteria or plants, to change their properties for a specific purpose. For example, crops can be modified to become more drought- or pest-resistant. Genetic engineering is a very powerful tool in biotechnology that has already found many different applications in agriculture, medicine, and industry. In this project, you will engineer a… Read more

Forensic Science: Building Your Own Tool for Identifying DNA

Science Fair Project Idea

Scientific Method

When biologists want to separate different pieces of DNA, RNA, or proteins they use a technique called gel electrophoresis. In this science project you'll build a gel electrophoresis chamber and use it to discover how many components are in different colors of food coloring dye. Read more

Enzyme-Catalyzed Reactions— What Affects Their Rates?

Science Fair Project Idea

Scientific Method

Enzymes speed up chemical reactions by factors of at least a million. Now that's acceleration! This project investigates how temperature affects how fast these enzymatic reactions occur. Read more

CRISPR Gene Editing of Escherichia coli

Science Fair Project Idea

Scientific Method

Many scientists are currently very excited about CRISPR, as it has the potential to revolutionize gene editing. But what exactly is CRISPR and what does it do? CRISPR is a novel tool in gene editing that allows the modification of genetic DNA at specific target sites in many different organisms. Researchers have high hopes that this technology can, one day, cure genetic diseases, as mutated DNA sequences can easily be corrected. In this project, you will use CRISPR to mutate a DNA sequence… Read more

Exploring DNA Damage: What Effect Do Ultraviolet Rays Have on Yeast Colony Growth?

Science Fair Project Idea

Scientific Method

Though the Sun provides heat and light, which are essential for life on Earth, ultraviolet (UV) rays in sunlight can cause damage to DNA. In this science fair project, you will experiment with a strain of yeast that is super-sensitive to UV light. This project will demonstrate the lethal effects of UV light when DNA damage is not repaired. Read more

Column Chromatography: Can you Separate the Dyes in Grape Soda Using Space Sand™?

Science Fair Project Idea

Scientific Method

What color is grape soda? If you pour it into a clear glass you can easily see it is purple, but that is usually not its natural color. Manufacturers add red and blue dye to the soda. The dyes mix together and you get purple soda. What if you wanted to un-mix the dyes, could you? Yes! In a chemistry laboratory, using a technique called column chromatography, you could separate the two dyes again. But what about at home, can you use low-tech supplies to do the same thing? In this science project… Read more

Purification Strategies

Science Fair Project Idea

Scientific Method

In order to study individual biochemical compounds like proteins, DNA, or RNA, biochemists need to know how to purify these components from a complex mixture. This is especially important for biotechnology and pharmaceutical industries, which sell purified biochemicals as reagents or drugs to consumers. Do an experiment to purify DNA, RNA, or protein from a complex mixture (for purifying DNA, see the Science Buddies project Extracting Onion DNA). The source of the material can be a cell… Read more

Catalytic RNA and Structure

Science Fair Project Idea

Scientific Method

Some sequences of RNA can catalyze biochemical reactions, much like protein enzymes. These catalytic RNA sequences are called ribozymes. The function of a ribozyme depends upon the primary sequence of the RNA which folds into a 3-D structure. How do different ribozyme sequences fold? You can search for ribozyme sequences using Entrez BLAST (NCBI, 2006). Then you can use a program like MFOLD (http://bioweb.pasteur.fr/seqanal/interfaces/mfold-simple.html) to submit your sequence for an… Read more

Turn Plants into Biofuel with the Power of Enzymes

Science Fair Project Idea

Scientific Method

Are biofuels the wave of the future? People often talk about these plant-derived fuels as a way to someday cut down on our dependency on non-renewable carbon-based fuels, like gasoline. Ethanol (a type of alcohol) is a common biofuel used today. In the United States, ethanol is a common biofuel additive to normal gasoline. In fact, some states mandate that when you fill up your gas tank, 10 percent of the total fuel volume be made of ethanol. Brazil, the world's second largest user of… Read more

Transforming Bacteria to Make Colored Pigments

Science Fair Project Idea

Scientific Method

Can bacteria be altered to produce life-saving insulin for diabetics? Or change color to indicate the presence of a harmful toxin? Yes, it can! Using biotechnology, scientists work daily on problems like these. It starts with selecting a gene you want bacteria to produce and creating a sequence of DNA that has that gene and a promoter that will help express it at the right time and at the right levels. The next hurdle is actually getting this engineered DNA into the bacteria and… Read more

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