Twelfth Grade, Microbiology Projects, Lessons, Activities (11 results)

Microorganisms are all around us, with an amazing diversity of adaptations. They were the first life on Earth, and their relatively recent discovery in extreme environments—like hot springs, ocean vents, and polar ice—illustrates how tenaciously they've evolved and survived. Microbiology gives us insights into evolution, disease, and even the mechanisms of our own cells.

Make Your Own Hand Sanitizer

STEM Activity

34 reviews

Did you ever wonder what hand sanitizer is made of, or how you can efficiently disinfect your hands or other frequently touched surfaces like doorknobs? Handwashing is still the best way to keep your hands clean, but hand sanitizer is a great alternative for situations where clean water and soap are not available, and you can even use it to disinfect surfaces! Intrigued—try out making a hand sanitizer yourself! Read more

Antibiotic Resistance

Science Fair Project Idea

Scientific Method

Antibiotics work by destabilizing the metabolism or cellular structure of bacteria, preventing growth, and causing bacteria to die. Some strains of bacteria have mutated and found a way to resist the actions of antibiotics. These are called resistant strains because they resist the actions of available antibiotic treatments. There are many different types of antibiotics that are continually being developed to combat new strains of resistant bacteria. Some antibiotics work better on different… Read more

What Sugar And Tea Does a Kombucha Biofilm Prefer?

Science Fair Project Idea

Scientific Method

You may have seen kombucha at the grocery store marketed as a healthy food choice. Did you know this drink is made with a special biofilm that ferments sugar into the tangy, fizzy drink? How does it do that? In this experiment, you'll learn how to make your own kombucha from a biofilm and what tea or sugar substrates you can change! Read more

Cinnamon Gum and Mouth Microbes

Science Fair Project Idea

Scientific Method

Did you know that a scientific study has shown that chewing Big Red Gum reduces mouth microbes? (ScienceDaily contributors, 2004) The cinnamon oil in the gum is a natural defense against mouth bacteria that cause tooth decay and bad breath. Conduct an experiment to compare products with cinnamon essence in gum, candy, toothpaste, and mouthwash to see if they can decrease mouth germs. Do a before and after swab of the mouth with a Q-tip. Which treatments work the best? Can you find another… Read more

Biowarfare: Experiment with Viruses that Destroy Bacteria

Science Fair Project Idea

Scientific Method

Most people are not aware that the soil around them is a battle scene. The combatants are very small—bacteria on one side and bacteriophage on the other. The bacteriophage (or phage for short) try to pierce the outer coats of the bacteria and inject them with phage DNA. If successful, the DNA will take over the inner machinery of the bacterial cells and force them to make many copies of the phage. After the copies are made, the bacterial cells break apart, releasing new phage that start… Read more

Do Different Dilutions of Disinfectants Affect the Development of Bacterial Resistance?

Science Fair Project Idea

Scientific Method

This is a project that illustrates the process of natural selection in action. You'll need access to a laboratory for working with the bacterial cultures used in this project. Read more

Natural Antimicrobial Agents

Science Fair Project Idea

Scientific Method

What do pneumonia, ear infections and strep throat have in common? When they are caused by bacteria (instead of viruses) they are treated by antibiotics. That sounds simple enough, right? You have probably had antibiotics several times in your life. You go to the doctor because you feel lousy, if he or she determines you have a bacterial infection you get a prescription for antibiotics, and within the first day or so you often start feeling much better. Unfortunately, there is a large… Read more

Preventing the Zombie Apocalypse- Making Gene Therapy Safe!

Lesson Plan Grade: 9th-12th

Students become biomedical engineers and create model viruses for use in therapeutic applications, such as gene therapy. In constructing their models, students carefully plan for side effects and modify a virus that can be used to safely to deliver gene therapy. This process involves taking a "wild type" (or unmodified) virus so it can target a specific area of the body.Engineering Connection Genetic engineering is the artificial manipulation, modification, and… Read more

NGSS Performance Expectations:

HS-ETS1-2. Design a solution to a complex real-world problem by breaking it down into smaller, more manageable problems that can be solved through engineering.

Minimizing Bacteria in the Thawing and Cooking of Meat

Science Fair Project Idea

Scientific Method

How does your family thaw and cook meat? Have you ever wondered if it is the safest way? In this practical science project, you can find out and shed light on safe practices in the kitchen by investigating how many viable bacteria are present in samples of meat that have been thawed or cooked using different methods. Read more

Slimey Likes It! Studying Chemotaxis in Physarum Polycephalum

Science Fair Project Idea

Scientific Method

In this biology science fair project, you will observe how the Physarum polycephalum (P. polycephalum) organism responds to various amounts of glucose. P. polycephalum is easy to grow in a petri dish and responds in complex ways to its environment. Will it grow toward the chemical as it looks for a meal, or will it flee, trying to avoid further contact? Try this science fair project to learn more about chemotaxis in the fascinating Physarum polycephalum. Read more

Explore Our Science Videos

Automatic Dog (or cat) Treat Dispenser with Arduino | Science Project

Cellular Respiration | STEM Lesson Plan Introduction

The Science of Frescoes – STEAM Activity