Science Buddies' twelfth grade science projects are the perfect way for twelfth grade students to have fun exploring science, technology, engineering, and math (STEM). Our twelfth grade projects are written and tested by scientists and are specifically created for use by students in the twelfth grade. Students can choose to follow the science experiment as written or put their own spin on the project.

For a personalized list of science projects, twelfth graders can use the Science Buddies Topic Selection Wizard. The wizard asks students to respond to a series of simple statements and then uses their answers to recommend age-appropriate projects that fit their interests.

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Using Vaccines to Fight Outbreaks
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Lesson Plan Grade: 6th-12th
What exactly is a vaccine? Can vaccines prevent outbreaks? How effective does a vaccine need to be to help a population during an outbreak? Students will explore these questions and more in this lesson plan by first learning the biology behind vaccines. They will then use SimPandemic, a free online tool, to model different vaccine parameters to understand how vaccines affect both individuals and populations during a COVID-19 outbreak. Remote learning adaptation: This lesson plan can be… Read more
NGSS Performance Expectations:
  • MS-LS2-1. Analyze and interpret data to provide evidence for the effects of resource availability on organisms and populations of organisms in an ecosystem.
  • MS-LS2-4. Construct an argument supported by empirical evidence that changes to physical or biological components of an ecosystem affect populations.
  • HS-LS2-8. Evaluate evidence for the role of group behavior on individual and species' chances to survive and reproduce.
Preventing Outbreaks with Herd Immunity
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Lesson Plan Grade: 6th-12th
What is herd immunity, how is it achieved, and what impact does it have on outbreaks? Students will explore these questions and more in this lesson plan. They will then use SimPandemic, a free online tool, to model different levels of viral immunity in communities to understand how a population can reach the herd immunity threshold and the impacts that has on individuals and populations during a COVID-19 outbreak. Remote learning adaptation: This lesson plan can be conducted remotely. … Read more
NGSS Performance Expectations:
  • MS-LS2-4. Construct an argument supported by empirical evidence that changes to physical or biological components of an ecosystem affect populations.
  • HS-LS2-8. Evaluate evidence for the role of group behavior on individual and species' chances to survive and reproduce.
Tallest Paper Tower Challenge for Grades 9-12
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Lesson Plan Grade: 9th-12th
Teach your students about the engineering design process with this fun lesson plan. The lesson is based on the real-world challenge of designing an observation tower. Can your students maximize the height of the tower while minimizing the amount of material needed to construct it? Optionally, students can enter their designs in the 2021 Fluor Engineering Challenge for a chance to win a cash prize for your school! Teachers, note that elementary and middle school versions of this lesson plan… Read more
NGSS Performance Expectations:
  • HS-ETS1-3. Evaluate a solution to a complex real-world problem based on prioritized criteria and trade-offs that account for a range of constraints, including cost, safety, reliability, and aesthetics as well as possible social, cultural, and environmental impacts.
Reaction Rates: Speed It Up with Temperature!
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Lesson Plan Grade: 9th-12th
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Teach your students how temperature affects chemical reaction rates in this highly visual experiment! Students will investigate color change during the reaction of food color with bleach, and measure the reaction times using Google's Science Journal app. Read more
NGSS Performance Expectations:
  • HS-PS1-5. Apply scientific principles and evidence to provide an explanation about the effects of changing the temperature or concentration of the reacting particles on the rate at which a reaction occurs.
How Big is Big? Understanding Scale in Nature
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Lesson Plan Grade: 6th-12th
Some organisms, like whales and redwood trees, are so large that it's hard for us to picture just how big they are! In this lesson, students practice mathematics and computational thinking to create scale models of themselves, and then apply these skills to create models of other large organisms. This activity works best when stretched out over three (or more) class periods. Read more
Could Climate Change Impact the Mosquito-Human Disease Ecosystem?
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Lesson Plan Grade: 6th-12th
Scientists are concerned that climate change could cause the spread of mosquito populations that carry diseases like malaria, West Nile virus, Zika virus, and dengue fever. In this lesson plan, your students will access real-world data on mosquitoes at different locations throughout the United States, and examine the effects of temperature on mosquito populations. Remote learning adaptation: This lesson plan can be conducted remotely. Students can work independently on the Explore section of… Read more
NGSS Performance Expectations:
  • MS-LS2-4. Construct an argument supported by empirical evidence that changes to physical or biological components of an ecosystem affect populations.
  • HS-LS2-1. Use mathematical and/or computational representations of phenomena or design solutions to support explanations of factors that affect carrying capacity of ecosystems at different scales.
Forces and Motion
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Lesson Plan Grade: 9th-12th
Students explore how force, mass, and acceleration are related in this hands-on lesson plan. By experimenting with pushing a box across the table while varying force and mass and measuring the box's acceleration with Google's Science Journal app, students discover Newton's second law of motion for themselves. Read more
NGSS Performance Expectations:
  • HS-PS2-1. Analyze data to support the claim that Newton's second law of motion describes the mathematical relationship among the net force on a macroscopic object, its mass, and its acceleration.
Reaction Rates: When Surface Area Matters!
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Lesson Plan Grade: 9th-12th
How does surface area affect the speed of a chemical reaction? Let your students find out in this sizzling lesson plan! In this project, they will explore this correlation by crushing Alka-Seltzer® tablets into different sized particles and measuring how long it takes for them to dissolve in water. Read more
NGSS Performance Expectations:
  • HS-PS1-5. Apply scientific principles and evidence to provide an explanation about the effects of changing the temperature or concentration of the reacting particles on the rate at which a reaction occurs.
Air Pressure, It's in the Bag
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Lesson Plan Grade: 6th-12th
In this activity, students are asked to create a change in air pressure using a garbage bag and vacuum cleaner, then create an illustration, model or concept map that explains what is happening. This activity is part of the KQED Engineering Is: Bringing Fish Up from the Deep e-book. The e-book explores the science and engineering principles behind the California Academy of Sciences' portable decompression chamber, and includes videos,… Read more
CUT! How Does CRISPR Work?
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Lesson Plan Grade: 6th-12th
In this lesson plan, students will take a closer look at the most recent developments in gene editing. Specifically, they will learn about the CRISPR technology using various interactive simulations and other resources. Based on their gained knowledge, students will create a model of the CRISPR-Cas9 components and create a stop-motion animation video of the molecular mechanism of CRISPR-Cas9. Remote learning adaptation: This lesson plan can be conducted remotely. Students can work… Read more
NGSS Performance Expectations:
  • MS-LS4-5. Gather and synthesize information about technologies that have changed the way humans influence the inheritance of desired traits in organisms.
  • HS-LS1-1. Construct an explanation, based on evidence, for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.
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