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High School Lesson Plans (70 results)

Science Buddies' high school science projects are the perfect way for high school students to have fun exploring science, technology, engineering, and math (STEM). Our high school projects are written and tested by scientists and are specifically created for use by students in the high school grades. Students can choose to follow the science experiment as written or put their own spin on the project.

For a personalized list of science projects, high schoolers can use the Science Buddies Topic Selection Wizard. The wizard asks students to respond to a series of simple statements and then uses their answers to recommend age-appropriate projects that fit their interests.

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Reaction Rates: When Surface Area Matters!
Lesson Plan Grade: 9th-12th
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4 reviews
How does surface area affect the speed of a chemical reaction? Let your students find out in this sizzling lesson plan! In this project, they will explore this correlation by crushing Alka-Seltzer® tablets into different sized particles and measuring how long it takes for them to dissolve in water. Read more
NGSS Performance Expectations:
  • HS-PS1-5. Apply scientific principles and evidence to provide an explanation about the effects of changing the temperature or concentration of the reacting particles on the rate at which a reaction occurs.
Control the Reaction Rate of a Foaming Reaction
Lesson Plan Grade: 9th-12th
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1 review
In this lesson, students will employ the enzymatic decomposition reaction of hydrogen peroxide to investigate how chemical reactions are affected by enzymes and different substrate concentrations. Students will be challenged to control the rate of the reaction by adjusting the amount of substrate and thus changing the catalase activity. Foam production, created by the enzymatic breakdown of hydrogen peroxide into water and oxygen, will function as a proxy for the reaction rate. Based on their… Read more
NGSS Performance Expectations:
  • HS-PS1-5. Apply scientific principles and evidence to provide an explanation about the effects of changing the temperature or concentration of the reacting particles on the rate at which a reaction occurs.
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CUT! How Does CRISPR Work?
Lesson Plan Grade: 6th-12th
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6 reviews
In this lesson plan, students will take a closer look at the most recent developments in gene editing. Specifically, they will learn about the CRISPR technology using various interactive simulations and other resources. Based on their gained knowledge, students will create a model of the CRISPR-Cas9 components and create a stop-motion animation video of the molecular mechanism of CRISPR-Cas9. Remote learning adaptation: This lesson plan can be conducted remotely. Students can work… Read more
NGSS Performance Expectations:
  • MS-LS4-5. Gather and synthesize information about technologies that have changed the way humans influence the inheritance of desired traits in organisms.
  • HS-LS1-1. Construct an explanation, based on evidence, for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.
Discover STEM Careers
Lesson Plan Grade: 6th-12th
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4 reviews
Each student will get the chance to identify their own uniquely interesting STEM careers by tapping into the insights of the Career Discovery Tool. Remote learning adaptation: This lesson plan can be conducted remotely. During the Engage section, students can "order" their favorite ice cream using a poll on video chat. During the Explore section, students can access the Career Discovery Tool remotely as long as they have a device and access to the Internet. They can complete the Explore… Read more
Introduction to Arduino
Lesson Plan Grade: 6th-12th
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10 reviews
This lesson plan will introduce your students to physical computing: the process of building circuits and programming a microcontroller (an Arduino UNO®) to interact with them. The lesson is broken into seven activities that will walk your students through the basics of setting up the Arduino and interacting with circuit parts like LEDs, buttons, and resistors. This introductory material will help prepare your students for more advanced Arduino projects. Read more
Using Green Chemistry to Understand Types of Chemical Reactions
Lesson Plan Grade: 9th-12th
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11 reviews
This lab discusses types of reactions and replaces traditional reaction experiments involving chemicals such as lead (II) nitrate, barium chloride, and silver nitrate with greener alternatives. This lab is designed to challenge students to identify types of chemical reactions and distinguish between those that use safer, less hazardous chemicals and those that are more dangerous. Students will make a choice as to which reaction they will perform using the 12 Principles of Green Chemistry. They… Read more
2026 Ball Run Challenge for Grades 9-12
Lesson Plan Grade: 9th-12th
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3 reviews
Add a twist to a classic activity with this fun lesson plan. Your students will design and build a ball run for a ping pong ball using nothing but paper and tape. Their goal is to make the slowest ball run possible. How long can they make it take for the ball to go through their ball run? An optional variation is available if you would like to give students an extra challenge. The 2026 Engineering Challenge has ended. You can still do this challenge with students informally. Read more
NGSS Performance Expectations:
  • High School - Science & Engineering Practices
Build an Arduino Mini-Drone
Lesson Plan Grade: 8th-12th
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2 reviews
In this STEM lesson, students will build a mini popsicle stick drone and use feedback control with an Arduino and an ultrasonic sensor to control the drone's altitude. Read more
Build an Arduino Self-Driving Car
Lesson Plan Grade: 8th-12th
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2 reviews
This eight-part lesson will guide you through building and programming Arduino-controlled autonomous cars with your students. Each part contains a detailed step-by-step video and a supplemental lesson plan PDF with learning objectives, assessment opportunities, and appendices with circuit diagrams and example code. You can present the material yourself or have students follow along with the videos and pause to work on their autonomous cars. Read more
NGSS Performance Expectations:
  • HS-ETS1-2. Design a solution to a complex real-world problem by breaking it down into smaller, more manageable problems that can be solved through engineering.
Design 'Y'er Genes
Lesson Plan Grade: 9th-12th
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3 reviews
This lesson introduces students to the relationships between chromosomes, genes, and DNA molecules. Using the example of a strawberry, it also provides activities that clearly show how changes in the DNA of an organism, either naturally or artificially, can cause changes. Read more
NGSS Performance Expectations:
  • HS-LS3-3. Heredity: Inheritance and Variation of Traits
    Apply concepts of statistics and probability to explain the variation and distribution of expressed traits in a population.
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