Twelfth Grade Lesson Plans (Page 3)

How Our Immune System and Vaccines Protect Us From Diseases

Lesson Plan Grade: 9th-12th

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What happens in our bodies when we get sick? How do vaccines protect us from certain diseases? These are some questions that students will learn to answer in this lesson plan. Through a series of activities, students will be introduced to our immune system. They will learn how vaccines make use of our adaptive immune response to fight diseases. Read more

Immunotherapy: How Antibodies Can Be Used to Treat Diseases

Lesson Plan Grade: 8th-12th

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In this lesson, students will do a series of activities to explore the role of antibodies in our immune system. They will also investigate how doctors use monoclonal antibodies as part of immunotherapy to treat diseases like cancer. Read more

Magnetic Fluids

Lesson Plan Grade: 9th-12th

In this fun, engaging activity, students are introduced to a unique type of fluid "ferrofluids" whose shape can be influenced by magnetic fields! Students act as materials engineers and create their own ferrofluids. They are challenged to make magnetic ink out of ferrofluids and test their creations to see if they work. Concurrently, they learn more about magnetism, surfactants and nanotechnology. As they observe fluid properties as a standalone-fluid and under an imposed… Read more

NGSS Performance Expectations:

HS-PS2-6.. Communicate scientific and technical information about why the molecular-level structure is important in the functioning of designed materials.

Make a Dye-Sensitized Solar Cell

Lesson Plan Grade: 9th-12th

How does a solar cell work? In this green chemistry lesson plan, students will build and test their own dye-sensitized solar cells using dye from blackberries. Along the way, they will learn about the principles of green chemistry and evaluate how solar cell manufacturing can go green. Read more

NGSS Performance Expectations:

HS-ESS3-2. Evaluate competing design solutions for developing, managing, and utilizing energy and mineral resources based on cost-benefit ratios.
HS-ESS3-4. Evaluate or refine a technological solution that reduces the impact of human activities on natural systems.

Make Mushroom Packaging to Explore Long-Term Ecological Impact

Lesson Plan Grade: 9th-12th

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Are your students passionate about the environment? Do they like to explore new ideas for more eco-friendly products? This lesson will give your students a chance to grow a product out of mycelium composite, a material that recently gained traction as an eco-friendly alternative for many plastics and foams. Students will analyze the impact of this product on the environment at every step of its life cycle, from raw material to the end of its life, and compare it to a plastic or cardboard… Read more

NGSS Performance Expectations:

HS-ESS3-4. Evaluate or refine a technological solution that reduces impacts of human activities on natural systems.

Model the Chances of Getting an Autoimmune Disease

Lesson Plan Grade: 9th-12th

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Can genetic or environmental factors affect our chances of getting a certain disease? In this activity, your students will model how an existing predisposition can impact the probability of developing an autoimmune disease using dice and M&M's® candy! Read more

NGSS Performance Expectations:

HS-LS3-3. Apply concepts of statistics and probability to explain the variation and distribution of expressed traits in a population.

Ping Pong Pickup Challenge for Grades 9-12

Lesson Plan Grade: 9th-12th

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In this fun engineering lesson plan, your students will build devices from paper, tape, string, and paper clips to pick up and retrieve a ping pong ball. The challenge is to pick up the ball from as far away as possible! Elementary school and middle school versions of this lesson plan are also available. The 2023 competition is over, but you can see what students built and learn about the winners on the 2023 Engineering Challenge summary page. Read more

NGSS Performance Expectations:

High School - Science & Engineering Practices

Protecting Nature with Technology

Lesson Plan Grade: 9th-12th

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You might have read about the negative impacts modern human civilization has had on the environment, like pollution, deforestation, and extinction of animal species. How can we use modern technology to help protect the environment? In this project-based lesson students will design an electronic circuit that can measure something in the environment like water quality and light pollution, and develop a plan for how their circuits could be used to solve a real-world problem. Read more

NGSS Performance Expectations:

HS-ESS3-4. Evaluate or refine a technological solution that reduces impacts of human activities on natural systems.

Rocket Catcher Challenge for Grades 9-12

Lesson Plan Grade: 9th-12th

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In this fun engineering lesson plan, your students will build a rocket-catching device to help a falling rocket land vertically without crashing, using simple and readily-available materials. Elementary and middle school versions of this lesson plan are also available. This lesson was part of the 2025 Science Buddies Engineering Challenge. Read more

NGSS Performance Expectations:

High School - Science & Engineering Practices

Rubber Band Car Challenge for Grades 9-12

Lesson Plan Grade: 9th-12th

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In this fun engineering lesson plan, your students will build rubber band-powered cars using readily available craft supplies. The challenge is to build a car that goes as far as possible while making careful use of materials. Elementary school and middle school versions of this lesson plan are also available. This lesson was part of the 2024 Science Buddies Engineering Challenge. Read more

NGSS Performance Expectations:

High School - Science & Engineering Practices

Twelfth Grade Lesson Plans (63 results)

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