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Ninth Grade, Medical Biotechnology Projects, Lessons, Activities (19 results)

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Science Fair Project Idea
Scientific Method
Antioxidants have become very popular in the news lately for their potential health and anti-aging properties. Antioxidants work by preventing oxidation reactions that produce free-radicals which can cause harm to the body. Try testing different vitamins for antioxidant activity. How do vitamins A, B, C, and E compare? Do some vitamins have more antioxidant activity than others? What are some other sources of antioxidants? Try testing extracts from proposed sources of antioxidants like coffee,… Read more
Lesson Plan Grade: 9th-12th
Students act as if they are biological engineers following the steps of the engineering design process to design and create protein models to replace the defective proteins in a child's body. Jumping off from a basic understanding of DNA and its transcription and translation processes, students learn about the many different proteins types and what happens if protein mutations occur. Then they focus on structural, transport and defense proteins during three challenges… Read more
NGSS Performance Expectations:
  • HS-LS1-1. Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells.
  • HS-LS1-2. Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.
  • HS-ETS1-2. Design a solution to a complex real-world problem by breaking it down into smaller, more manageable problems that can be solved through engineering.
  • HS-ETS1-3. Evaluate a solution to a complex real-world problem based on prioritized criteria and trade-offs that account for a range of constraints, including cost, safety, reliability, and aesthetics, as well as possible social, cultural, and environmental impacts.
STEM Activity
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Biologic manufacturing is a multi-step process for creating a biological product that can help reduce symptoms or treat a disease. Below is an image of an overview of the drug development process you will be modeling. Figure 1. Overview of the basic steps of the biologic development process modeled in this activity. Read more
Lesson Plan Grade: 8th-12th
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In this lesson, students will do a series of activities to explore the role of antibodies in our immune system. They will also investigate how doctors use monoclonal antibodies as part of immunotherapy to treat diseases like cancer. Read more
Lesson Plan Grade: 9th-12th
Students create large-scale models of microfluidic devices using a process similar to that of the PDMS and plasma bonding that is used in the creation of lab-on-a-chip devices. They use disposable foam plates, plastic bendable straws and gelatin dessert mix. After the molds have hardened overnight, they use plastic syringes to inject their model devices with colored fluid to test various flow rates. From what they learn, students are able to answer the challenge question… Read more
NGSS Performance Expectations:
  • HS-ETS1-2. Design a solution to a complex real-world problem by breaking it down into smaller, more manageable problems that can be solved through engineering.
Lesson Plan Grade: 6th-9th
In this lesson plan, students will model the complex biologic manufacturing process. First, they will model the cellular expansion process that occurs in a bioreactor. Then, students will lyse the cells to isolate the proteins from the dyed cell debris. Lastly, they will model the advanced filtration process to purify proteins so they can be used as medicines. Read more
NGSS Performance Expectations:
  • MS-LS1-2. Develop and use a model to describe the function of a cell as a whole and ways the parts of cells contribute to the function.
Lesson Plan Grade: 9th-12th
Students become biomedical engineers and create model viruses for use in therapeutic applications, such as gene therapy. In constructing their models, students carefully plan for side effects and modify a virus that can be used to safely to deliver gene therapy. This process involves taking a "wild type" (or unmodified) virus so it can target a specific area of the body.Engineering Connection Genetic engineering is the artificial manipulation, modification, and… Read more
NGSS Performance Expectations:
  • HS-ETS1-2. Design a solution to a complex real-world problem by breaking it down into smaller, more manageable problems that can be solved through engineering.
Science Fair Project Idea
Scientific Method
Have you ever wondered where acne comes from and how you can treat it? One major cause of acne is the colonization and infection of clogged pores with bacteria. In this science project, you'll test different acne medications and treatments to determine their effectiveness at killing bacteria. Read more
Science Fair Project Idea
Scientific Method
Have you ever wondered how antibiotics and other medicines are able to stop dangerous infections? How do such medications kill microorganisms without in general harming the person the microorganisms are infecting? Because many different types of microorganisms can infect us, we have had to develop an amazing number of ways to deal with these harmful microbes. Fungal infections can be particularly dangerous, but we have developed many different antifungal medications that can usually deal with… Read more
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