High School Science Projects (Page 20)

CRISPR Gene Editing of Escherichia coli

Science Fair Project Idea

Scientific Method

Many scientists are currently very excited about CRISPR, as it has the potential to revolutionize gene editing. But what exactly is CRISPR and what does it do? CRISPR is a novel tool in gene editing that allows the modification of genetic DNA at specific target sites in many different organisms. Researchers have high hopes that this technology can, one day, cure genetic diseases, as mutated DNA sequences can easily be corrected. In this project, you will use CRISPR to mutate a DNA sequence… Read more

Balls Bouncing Off of Surfaces

Science Fair Project Idea

Scientific Method

For example, think of hitting a baseball, heading a soccer ball into the net, or hitting a tennis ball with a racquet. Where the ball goes depends on...what? You can set up a simple model to start your investigation. You'll need a marble, a flat piece of wood, a flat piece of cardboard, a pencil, a ruler, a protractor, and a level surface. Lay down the cardboard down on a level surface and set up the flat piece of wood at one edge. The wood will act like a wall, and you're going to roll… Read more

Why Does the Moon Appear Larger at Some Times?

Science Fair Project Idea

Scientific Method

Some claim the Moon appears larger when near the horizon. Make a series of observations of the Moon, measuring the Moon's angular diameter each time. You should also note the Moon's altitude above the horizon, and the Moon's phase. You should do background research on the lunar orbit to determine the necessary time period. Do you find predictable variations in the Moon's diameter? Can you relate this to the Moon's changing distance from Earth? From your data, try to determine when apogee and… Read more

Materials for Sound Barriers

Science Fair Project Idea

Scientific Method

What are the best materials to use for blocking out unwanted noise from the environment? You can build a test box (or test frame) around an audio speaker. Use a sound level meter to measure the speaker output. Use different materials to cover the walls of your test box (or frame), and see which materials do the best job at blocking the sound. For a more advanced project, perform your tests using different sound frequencies. Are some materials better at blocking certain frequencies than… Read more

What's the Fastest Way to Sort a List?

Science Fair Project Idea

Scientific Method

Imagine that you have a list of names of all the people in your class. Someone asks you to put them in alphabetical order. How would you go about doing it? Would you first go through the entire list and look for all the "A" names? Then go through it again and look for all the "B" names, and so on? Do you think going through the list over and over again for each letter would be inefficient? What if you had hundreds, thousands, or even millions of names? How would you ever alphabetize them… Read more

Delayed Release Pill Challenge: Getting Medicine to the Right Place at the Right Time

Science Fair Project Idea

Engineering Design Process

A lot of medication comes in the form of pills that you need to swallow. But not all pills are the same! Some look like little capsules, others are made of pressed powder. Why are there different types of pills? Different types of pills release their active ingredients in different ways. Some release their active ingredient right after initial administration. Others release their active ingredient much later. Such drugs are called delayed-release drugs. These kinds of pills have to be… Read more

Drug Solubility

Science Fair Project Idea

Scientific Method

When you take medicine, it needs to dissolve in order to be passed into your bloodstream to have an effect. On the other hand, the drug needs to be packed into a small, dense pill to make it easier to swallow. How does the delivery method of a drug change how quickly it enters the bloodstream? Compare different brands of a drug to find out which brands dissolve the quickest. Does the pH of the stomach (which is usually between 1 and 2) matter? Compare coated to uncoated pills: does the coating… Read more

What Makes a Team's Winning Percentage Deviate from the Pythagorean Relationship?

Science Fair Project Idea

Scientific Method

What makes a winning team? Getting all the best players? Good coaches? Good chemistry? This project will show you how you can use math to help you test your hypothesis about what makes a winning team. The Pythagorean relationship is a fundamental one in sports: it correctly predicts the records of 98% of all teams. But in 2% of cases, it fails. Why does it fail? Find teams that deviated substantially from their expected Pythagorean record (this information is available for baseball teams… Read more

Exploring DNA Damage: What Effect Do Ultraviolet Rays Have on Yeast Colony Growth?

Science Fair Project Idea

Scientific Method

Though the Sun provides heat and light, which are essential for life on Earth, ultraviolet (UV) rays in sunlight can cause damage to DNA. In this science fair project, you will experiment with a strain of yeast that is super-sensitive to UV light. This project will demonstrate the lethal effects of UV light when DNA damage is not repaired. Read more

Yeast Busters: Stopping Fungus in its Tracks with Antifungal Medicines

Science Fair Project Idea

Scientific Method

Have you ever wondered how antibiotics and other medicines are able to stop dangerous infections? How do such medications kill microorganisms without in general harming the person the microorganisms are infecting? Because many different types of microorganisms can infect us, we have had to develop an amazing number of ways to deal with these harmful microbes. Fungal infections can be particularly dangerous, but we have developed many different antifungal medications that can usually deal with… Read more

High School Science Projects (695 results)

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