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Middle School, Medical Biotechnology Science Projects (17 results)

You already know that medicines like antibiotics and aspirin can make you feel better when you are sick, but how do researchers find new medicines? Do medications work the same way for everyone? How can we use medicine to treat genetic diseases?

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A Prescription for Success: Drugs & Your Genetics
Science Fair Project Idea
Scientific Method
Have you ever known someone who had a bad reaction to a prescription drug? Although pharmaceutical companies test new drugs on a large number of people to make sure the drug works the way it is supposed to, often a small percentage of people respond differently to the drug. A person's genetics plays a large role in determining his or her response to a given drug. Our genes are made up of hundreds to millions of nucleotides of DNA (deoxyribonucleic acid), the genetic code. If just a single… Read more
Antioxidants
Science Fair Project Idea
Scientific Method
Antioxidants have become very popular in the news lately for their potential health and anti-aging properties. Antioxidants work by preventing oxidation reactions that produce free-radicals which can cause harm to the body. Try testing different vitamins for antioxidant activity. How do vitamins A, B, C, and E compare? Do some vitamins have more antioxidant activity than others? What are some other sources of antioxidants? Try testing extracts from proposed sources of antioxidants like coffee,… Read more
Bioprinting: 3D Print with Living Cells! No 3D Printer Required.
Science Fair Project Idea
Scientific Method
Do you get excited about 3D printing technology? Do you like to think about other applications for this technology? 3D printing techniques can also be used with living cells, a method called 3D bioprinting. In this science project, you will explore 3D bioprinting a gelatinous substance with plant seeds. This process is similar to real 3D bioprinting techniques being explored to create tissues and organs. Read more
Build Your Own Microfluidic Device
Science Fair Project Idea
Engineering Design Process
Microfluidic devices are small tools used in different fields like engineering and biomedicine. Scientists and engineers use these devices to work with very tiny amounts of fluids for various experiments. These experiments can include things like biomedical research, creating new medicines, and even applications in the car industry. In this project, you will create and test your own microfluidic device design and compare it to other designs. Read more
Crime Scene Chemistry: The Kastle-Meyer Test for Blood
Science Fair Project Idea
Scientific Method
Police detectives use various scientific tools to analyze evidence at a crime scene. One of the classic tools is the Kastle-Meyer test for the presence of blood. This test is inexpensive, easy to perform, and provides quick results. The test provides evidence if red spots found at a crime scene are actually blood. But the investigator needs to be careful, since other substances can also give a positive result. In this crime scene chemistry science project, you will learn how to perform the… Read more
Delayed Release Pill Challenge: Getting Medicine to the Right Place at the Right Time
Science Fair Project Idea
Engineering Design Process
A lot of medication comes in the form of pills that you need to swallow. But not all pills are the same! Some look like little capsules, others are made of pressed powder. Why are there different types of pills? Different types of pills release their active ingredients in different ways. Some release their active ingredient right after initial administration. Others release their active ingredient much later. Such drugs are called delayed-release drugs. These kinds of pills have to be… Read more
Drug Solubility
Science Fair Project Idea
Scientific Method
When you take medicine, it needs to dissolve in order to be passed into your bloodstream to have an effect. On the other hand, the drug needs to be packed into a small, dense pill to make it easier to swallow. How does the delivery method of a drug change how quickly it enters the bloodstream? Compare different brands of a drug to find out which brands dissolve the quickest. Does the pH of the stomach (which is usually between 1 and 2) matter? Compare coated to uncoated pills: does the coating… Read more
Drugs & Genetics: Why Do Some People Respond to Drugs Differently than Others?
Science Fair Project Idea
Scientific Method
In a survey conducted from 2007 to 2010, the U.S. Centers for Disease Control and Prevention reported that about 49% of people in the United States had taken at least one prescription drug during the past month, and about 22% of people had taken three or more prescription drugs. People are prescribed drugs all the time, but prescriptions can be dangerous because people can have different responses to drugs. These responses largely have to do with genetic mutations. Why are some genetic… Read more
Fighting the Flu: How Your Immune System Uses Its Memory
Science Fair Project Idea
Scientific Method
Being sick is no fun, especially when your friends are doing exciting activities that you have to miss out on. Thankfully, common illnesses usually last for just a few days, and then you start to feel better. Why is this? It is thanks to the immune system, which is a group of special organs and cells in your body that constantly work to keep you healthy. In this science project, you will make a simple model to investigate how the immune system defends the human body from common illnesses, and… Read more
From Genes to Genetic Diseases: What Kinds of Mutations Matter?
Science Fair Project Idea
Scientific Method
Our genes are made up of hundreds to millions of building blocks, called DNA nucleotides, and if just a single nucleotide of DNA becomes mutated it might cause a devastating genetic disease. But sometimes a mutation actually does no damage. What kinds of mutations have to occur to cause a genetic disease? In this science project, you will explore online genetic databases to identify how a mutation in a gene can result in a dysfunctional protein, and how other mutations may have no effect at all. Read more
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