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Medical Biotechnology Lesson Plans (4 results)

You already know that medicines like antibiotics and aspirin can make you feel better when you are sick, but how do researchers find new medicines? Do medications work the same way for everyone? How can we use medicine to treat genetic diseases?

Lesson Plan Grade: 9th-12th
Students act as if they are biological engineers following the steps of the engineering design process to design and create protein models to replace the defective proteins in a child's body. Jumping off from a basic understanding of DNA and its transcription and translation processes, students learn about the many different proteins types and what happens if protein mutations occur. Then they focus on structural, transport and defense proteins during three challenges… Read more
NGSS Performance Expectations:
  • HS-LS1-1. Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells.
  • HS-LS1-2. Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.
  • HS-ETS1-2. Design a solution to a complex real-world problem by breaking it down into smaller, more manageable problems that can be solved through engineering.
  • HS-ETS1-3. Evaluate a solution to a complex real-world problem based on prioritized criteria and trade-offs that account for a range of constraints, including cost, safety, reliability, and aesthetics, as well as possible social, cultural, and environmental impacts.
Lesson Plan Grade: 9th-12th
Students become biomedical engineers and create model viruses for use in therapeutic applications, such as gene therapy. In constructing their models, students carefully plan for side effects and modify a virus that can be used to safely to deliver gene therapy. This process involves taking a "wild type" (or unmodified) virus so it can target a specific area of the body.Engineering Connection Genetic engineering is the artificial manipulation, modification, and… Read more
NGSS Performance Expectations:
  • HS-ETS1-2. Design a solution to a complex real-world problem by breaking it down into smaller, more manageable problems that can be solved through engineering.
Lesson Plan Grade: 6th-8th
Students use their knowledge about how healthy heart valves function to design, construct and implant prototype replacement mitral valves for hypothetical patients' hearts. Building on what they learned in the associated lesson about artificial heart valves, combined with the testing and scoring of their prototype heart valve designs in this activity, students discover the pros and cons of different types of artificial heart valves based on materials, surgery… Read more
NGSS Performance Expectations:
  • MS-ETS1-1. Define the criteria and constraints of a design problem with sufficient precision to ensure a successful solution, taking into account relevant scientific principles and potential impacts on people and the natural environment that may limit possible solutions.
  • MS-ETS1-2. Evaluate competing design solutions using a systematic process to determine how well they meet the criteria and constraints of the problem.
  • MS-ETS1-4. Develop a model to generate data for iterative testing and modification of a proposed object, tool, or process such that an optimal design can be achieved.
Lesson Plan Grade: 9th-12th
Students create large-scale models of microfluidic devices using a process similar to that of the PDMS and plasma bonding that is used in the creation of lab-on-a-chip devices. They use disposable foam plates, plastic bendable straws and gelatin dessert mix. After the molds have hardened overnight, they use plastic syringes to inject their model devices with colored fluid to test various flow rates. From what they learn, students are able to answer the challenge question… Read more
NGSS Performance Expectations:
  • HS-ETS1-2. Design a solution to a complex real-world problem by breaking it down into smaller, more manageable problems that can be solved through engineering.
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