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Middle School, Medical Biotechnology Projects, Lessons, Activities (21 results)

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Science Fair Project Idea
Scientific Method
Do you know someone who has an autoimmune disease? Autoimmune diseases are fairly common, affecting more than 23.5 million people in the United States, which is about 1 in 13 people! You may have heard of some of them, such as diabetes (type 1), rheumatoid arthritis, and celiac disease. Many autoimmune diseases are poorly understood, but they all have one thing in common: they happen because a person's immune system (which normally fights off germs to keep the person healthy) attacks the… Read more
Science Fair Project Idea
Engineering Design Process
Microfluidic devices are small tools used in different fields like engineering and biomedicine. Scientists and engineers use these devices to work with very tiny amounts of fluids for various experiments. These experiments can include things like biomedical research, creating new medicines, and even applications in the car industry. In this project, you will create and test your own microfluidic device design and compare it to other designs. Read more
Science Fair Project Idea
Scientific Method
Have you ever heard about different blood types? Do you know what your blood type is? Antibodies help scientists determine different human blood types. This project is a practical introduction to the human immune system in which you will learn about what antibodies are, how they are formed, and how they can be used to identify different types of cells. Read more
Science Fair Project Idea
Scientific Method
Have you ever wondered where acne comes from and how you can treat it? One major cause of acne is the colonization and infection of clogged pores with bacteria. In this science project, you'll test different acne medications and treatments to determine their effectiveness at killing bacteria. Read more
Science Fair Project Idea
Scientific Method
Antioxidants have become very popular in the news lately for their potential health and anti-aging properties. Antioxidants work by preventing oxidation reactions that produce free-radicals which can cause harm to the body. Try testing different vitamins for antioxidant activity. How do vitamins A, B, C, and E compare? Do some vitamins have more antioxidant activity than others? What are some other sources of antioxidants? Try testing extracts from proposed sources of antioxidants like coffee,… Read more
STEM Activity
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Biologic manufacturing is a multi-step process for creating a biological product that can help reduce symptoms or treat a disease. Below is an image of an overview of the drug development process you will be modeling. Figure 1. Overview of the basic steps of the biologic development process modeled in this activity. Read more
Science Fair Project Idea
Scientific Method
Have you ever known someone who had a bad reaction to a prescription drug? Although pharmaceutical companies test new drugs on a large number of people to make sure the drug works the way it is supposed to, often a small percentage of people respond differently to the drug. A person's genetics plays a large role in determining his or her response to a given drug. Our genes are made up of hundreds to millions of nucleotides of DNA (deoxyribonucleic acid), the genetic code. If just a single… Read more
Lesson Plan Grade: 8th-12th
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In this lesson, students will do a series of activities to explore the role of antibodies in our immune system. They will also investigate how doctors use monoclonal antibodies as part of immunotherapy to treat diseases like cancer. Read more
Lesson Plan Grade: 6th-9th
In this lesson plan, students will model the complex biologic manufacturing process. First, they will model the cellular expansion process that occurs in a bioreactor. Then, students will lyse the cells to isolate the proteins from the dyed cell debris. Lastly, they will model the advanced filtration process to purify proteins so they can be used as medicines. Read more
NGSS Performance Expectations:
  • MS-LS1-2. Develop and use a model to describe the function of a cell as a whole and ways the parts of cells contribute to the function.
Lesson Plan Grade: 6th-8th
Students use their knowledge about how healthy heart valves function to design, construct and implant prototype replacement mitral valves for hypothetical patients' hearts. Building on what they learned in the associated lesson about artificial heart valves, combined with the testing and scoring of their prototype heart valve designs in this activity, students discover the pros and cons of different types of artificial heart valves based on materials, surgery requirements,… Read more
NGSS Performance Expectations:
  • MS-ETS1-1. Define the criteria and constraints of a design problem with sufficient precision to ensure a successful solution, taking into account relevant scientific principles and potential impacts on people and the natural environment that may limit possible solutions.
  • MS-ETS1-2. Evaluate competing design solutions using a systematic process to determine how well they meet the criteria and constraints of the problem.
  • MS-ETS1-4. Develop a model to generate data for iterative testing and modification of a proposed object, tool, or process such that an optimal design can be achieved.
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